• The big one is Visual Studio 2008. It has been released including Express Editions. You definitely want to check this out at msdn.com/express.
• Also, for you math heads out there, check out the new Word 2007 add-in, "Microsoft Math". Get it at download.microsoft.com - search for officemath.
• For all you who have lamented about having to fill the same forms over and over at the doctor's office, check out HealthVault (healthvault.com). It is a platform for holding personal information (like the usual stuff you fill out on those forms) and holding ongoing data (like blood glucose levels synced from compatible monitors). You can choose what data to share with whom, for example, you can share your heart rate data to your exercise group or family to show your progress.
• For the bean counters, there's Office Accounting 2008, including an Express edition. This new version includes online banking service integration. If you're running or thinking about Intuit's Quikbooks, check this out at office.microsoft.com/accounting.
• Search Server 2008 now includes an Express edition. This gives you web search of your web and disk content. The release candidate is available at microsoft.com/enterprisesearch
• SQL Server 2008 November CTP - microsoft.com/sql

I normally scoff at blogs that are nothing but repeaters for Microsoft's marketing department, so I've tried to keep the descriptions unhyped. Additionally, these are all things I will be working with in the near future, so expect to see more information related to these soon.